“PMDD is not simply a more intense version of PMS. PMDD can significantly impact your life. The symptoms experienced, both physical and emotional, can be overwhelming. It’s important to know you do not have to struggle with this on your own. Talk to your healthcare provider about treatment options.”
— Jill E. Daino, LCSW-R, Talkspace therapist
Symptoms of PMDD
Emotional Symptoms
- Dramatic mood swings
- Feeling unusually emotional and crying easily
- Lack of energy
- Feeling “on edge”
- Inability to focus or difficulty concentrating
- Loss of interest in previously enjoyable activities
- Anxiety and tension
- Anger and irritability
- Feeling totally out of control or overwhelmed
- Negative or suicidal thoughts
Physical Symptoms
- Joint and muscle pain
- Breast tenderness
- Bloating
- Headaches
- Trouble sleeping or sleeping too much
- Changes in appetite and cravings
Causes of PMDD
The exact cause is not fully understood. Most researchers believe PMDD is due to extreme sensitivity to hormonal fluctuations — specifically estrogen and progesterone — rather than the hormone levels themselves. A woman is more likely to develop PMDD if her mother, sister, or close relative also has the condition. Cigarette smoking and a history of physical or emotional trauma are additional contributing factors.
“While research is still emerging around the causes for PMDD, it’s important to note that genetics likely play a role. Tracking your symptoms over time will help you discuss them with your healthcare provider and help you plan your self care and medical strategies in advance.”
— Jill E. Daino, LCSW-R, Talkspace therapist
Treatment for of PMDD
Treatment focuses on minimizing or eliminating symptoms. A doctor typically works with a mental health provider to build an individualized plan. You don’t have to suffer without help.
- Therapy: Counseling helps develop communication and coping skills for navigating PMDD symptoms. CBT has been explored, though evidence specific to PMDD is still developing. Online therapy is a convenient and accessible option.
- SSRIs: The most commonly prescribed medications for PMDD. Research shows 60–75% of women saw significant improvement. Examples: Prozac / Sarafem (fluoxetine) and Zoloft (sertraline).
- Oral contraceptives: Standard birth control pills do not alleviate PMDD, but those containing Ethinyl estradiol and drospirenone can help. Yaz is the only FDA-approved oral contraceptive for PMDD in the U.S.
- Anti-inflammatory medications: For headaches, muscle pain, and joint pain.
- Lifestyle changes: Avoiding triggering foods (sugar, salt, chocolate, caffeine, alcohol); daily exercise (releases serotonin naturally); high-protein diet; stress management via meditation, yoga, journaling, and deep breathing.






