Premenstrual Dysphoric Disorder (PMDD)

Written by

Published Aug 18, 2022

Clinically reviewed by

Reviewed Aug 18, 2022

Overview

  • Premenstrual dysphoric disorder (PMDD) is an extreme type of PMS — a mood disorder causing intense emotional and physical symptoms that can begin up to two weeks before menstruation. An estimated 5–8% of women live with PMDD.
  • PMDD is far more severe than PMS. While 90% of women experience some PMS, the difference isn’t hormone levels — it’s sensitivity. Two women can have identical estrogen and progesterone levels yet one has PMS while the other has PMDD.
  • Symptoms span both emotional (mood swings, anxiety, suicidal thoughts in severe cases) and physical (joint pain, bloating, headaches) categories, beginning up to two weeks before menstruation.
  • PMDD is listed in the DSM-5 as a mental health condition — despite its hormonal origins — because it causes wide-ranging psychiatric symptoms including depression, anxiety, and in extreme cases, suicidal thoughts.
  • Causes are not fully understood but involve extreme sensitivity to hormonal fluctuations. Genetics, smoking, and a history of trauma are contributing factors.
  • PMDD is treatable. SSRIs, oral contraceptives, counseling, and lifestyle changes are all effective approaches. Online therapy is a convenient option for women with busy schedules.
“PMDD is not simply a more intense version of PMS. PMDD can significantly impact your life. The symptoms experienced, both physical and emotional, can be overwhelming. It’s important to know you do not have to struggle with this on your own. Talk to your healthcare provider about treatment options.”

— Jill E. Daino, LCSW-R, Talkspace therapist

Symptoms of PMDD

Emotional Symptoms

  • Dramatic mood swings
  • Feeling unusually emotional and crying easily
  • Lack of energy
  • Feeling “on edge”
  • Inability to focus or difficulty concentrating
  • Loss of interest in previously enjoyable activities
  • Anxiety and tension
  • Anger and irritability
  • Feeling totally out of control or overwhelmed
  • Negative or suicidal thoughts

Physical Symptoms

  • Joint and muscle pain
  • Breast tenderness
  • Bloating
  • Headaches
  • Trouble sleeping or sleeping too much
  • Changes in appetite and cravings

Causes of PMDD

The exact cause is not fully understood. Most researchers believe PMDD is due to extreme sensitivity to hormonal fluctuations — specifically estrogen and progesterone — rather than the hormone levels themselves. A woman is more likely to develop PMDD if her mother, sister, or close relative also has the condition. Cigarette smoking and a history of physical or emotional trauma are additional contributing factors.

“While research is still emerging around the causes for PMDD, it’s important to note that genetics likely play a role. Tracking your symptoms over time will help you discuss them with your healthcare provider and help you plan your self care and medical strategies in advance.”

— Jill E. Daino, LCSW-R, Talkspace therapist

Treatment for of PMDD

Treatment focuses on minimizing or eliminating symptoms. A doctor typically works with a mental health provider to build an individualized plan. You don’t have to suffer without help.

  • Therapy: Counseling helps develop communication and coping skills for navigating PMDD symptoms. CBT has been explored, though evidence specific to PMDD is still developing. Online therapy is a convenient and accessible option.
  • SSRIs: The most commonly prescribed medications for PMDD. Research shows 60–75% of women saw significant improvement. Examples: Prozac / Sarafem (fluoxetine) and Zoloft (sertraline).
  • Oral contraceptives: Standard birth control pills do not alleviate PMDD, but those containing Ethinyl estradiol and drospirenone can help. Yaz is the only FDA-approved oral contraceptive for PMDD in the U.S.
  • Anti-inflammatory medications: For headaches, muscle pain, and joint pain.
  • Lifestyle changes: Avoiding triggering foods (sugar, salt, chocolate, caffeine, alcohol); daily exercise (releases serotonin naturally); high-protein diet; stress management via meditation, yoga, journaling, and deep breathing.

Learn more about PMDD

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Bisma Anwar, MA, MSc, LMHC

Bisma Anwar, MA, MSc, LMHC

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Jill E. Daino, LCSW-R

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What are the common signs of PMDD?

The most recognizable signs are severe emotional and physical symptoms that appear cyclically — beginning up to two weeks before menstruation and resolving around the start of the period. Emotional signs include dramatic mood swings, intense anxiety, anger or irritability, crying easily, loss of interest in activities, difficulty concentrating, feeling out of control, and in severe cases, suicidal thoughts. Physical signs include joint and muscle pain, breast tenderness, bloating, headaches, sleep changes, and appetite changes. A critical distinguishing feature: PMDD symptoms are severe enough to impair functioning at work, school, or in relationships — setting it apart from typical PMS.

How do you get diagnosed with PMDD?

PMDD is diagnosed using DSM-5 criteria. A woman must experience five or more specific symptoms during most menstrual cycles over a year, with at least one being from the first four on the list (depressed mood, anxiety/tension, affective lability, or persistent anger/irritability). Symptoms must be severe enough to impair functioning and not be explainable by another condition such as clinical depression, anxiety disorder, or bipolar disorder. As part of the diagnostic process, a clinician will interview you about your symptoms and review your medical history. Tracking symptoms across cycles before your appointment is highly recommended.

Who can diagnose PMDD?

Psychiatrists, psychologists, licensed clinical therapists, gynecologists, and primary care physicians are all qualified to diagnose PMDD. Because PMDD sits at the intersection of hormonal and mental health, a collaborative approach between a doctor and mental health provider is often ideal. A mental health professional experienced with mood disorders and women’s health is best positioned to evaluate the psychiatric symptom criteria required by the DSM-5.

Can an online therapist diagnose PMDD?

Yes. Licensed therapists and psychiatrists practicing via telehealth can evaluate and diagnose PMDD. Online therapy is an especially practical option for women managing busy schedules, and the counseling approaches most effective for PMDD are fully available in online formats.

What type of therapy is best for PMDD?

Counseling — focused on building communication skills and coping strategies for navigating severe PMDD symptoms — is the primary therapeutic approach. CBT has been explored for PMDD, though research on its specific effectiveness is still developing. Online therapy platforms offer convenient access for women with demanding schedules. In most cases, therapy is most effective when combined with medication for moderate-to-severe PMDD. A doctor and mental health provider working together typically produces the best outcomes.

When should you seek professional help for PMDD?

Seek help if cyclical emotional or physical symptoms are significantly disrupting your work, relationships, or daily life — especially if you feel like you spend two weeks managing symptoms and then two weeks repairing the damage before the cycle starts again. Don’t wait for symptoms to become unmanageable. If you are experiencing suicidal thoughts during your premenstrual phase, seek help immediately. Tracking your symptoms across at least two cycles before your first appointment will help your provider evaluate the pattern.

Can PMDD be treated?

Yes. PMDD is treatable, and effective options are available. SSRIs show a 60–75% (https://www.uptodate.com/contents/premenstrual-syndrome-pms-and-premenstrual-dysphoric-disorder-pmdd-beyond-the-basics#H12) improvement rate. Oral contraceptives (particularly Yaz, the only FDA-approved option) can help regulate mood and physical symptoms. Counseling and lifestyle changes — diet, exercise, and stress management — also play an important supporting role. Most treatment plans combine more than one approach. You don’t have to continue suffering month after month.

Does PMDD get worse over time?

For some women, PMDD symptoms — both physical and emotional — can steadily worsen over time until menopause. Some women experience a sharp increase in symptoms as they reach perimenopause.

How can I get help for PMDD?

Talk with your doctor or mental health professional about treatment options. Online therapy is a particularly accessible option for women with busy schedules, offering the flexibility to get support when and where you need it.

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